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The Real Causes of Hair Loss in Women Over 40

Hair loss after 40 is more common than many women realize. Female hair loss is a common concern for women over 40, affecting a significant number due to various factors.

Whether you are seeing extra strands in the shower drain or experiencing gradual thinning at your part line, these changes often trace back to specific causes related to age, hormones, or medical conditions.

Understanding what triggers hair loss in women over 40 is the first step to finding a treatment that supports lasting hair regrowth and improves self-esteem.

Why Does Hair Start Thinning After 40?

By your 40s, your hair has gone through hundreds of growth cycles. Hair follicles move through three cycles: anagen (growth), catagen (transition), and telogen (resting/shedding). With age, hair follicles can shrink or become more sensitive to hormonal shifts and environmental factors. As a result, the hair cycle becomes disrupted. More hairs enter the telogen phase or resting phase, and fewer remain in the anagen phase, where hair grows.

For many women, this leads to gradual thinning, weaker hairs, and hair shedding that may begin as subtle but eventually becomes more noticeable. Compared to male pattern baldness, which often affects the hairline, female pattern baldness shows up as overall thinning across the scalp or widening at the part.

1. Hormonal Shifts and Androgenetic Alopecia

As estrogen and progesterone levels drop during perimenopause and menopause, hormone imbalance can impact the normal hair cycle. Hormone changes, including fluctuations in estrogen, progesterone, and androgens, are a key factor in hair loss during this time. At the same time, androgen levels such as testosterone can increase in activity. Androgens, sometimes called male hormones, are present in both men and women and play a significant role in hair loss in women. This shift plays a role in female pattern hair loss, also known as androgenetic alopecia.

This condition causes hair follicles to shrink over time, leading to finer, shorter strands and slower regrowth. The result is overall thinning and decreased density. In your 40s hair loss starts to become more noticeable, especially at the crown and part line.

In many cases, treating FPHL early can help restore hair growth before follicles permanently close. Ultimately, hair loss depends on the specific hormone changes and individual factors affecting each person.

2. Thyroid Problems and Hair Shedding

The thyroid gland helps regulate metabolism, body temperature, and hormone levels. Thyroid problems like hypothyroidism or hyperthyroidism can shorten the anagen phase, slow hair growth, and cause diffuse thinning or bald spots.

If you are losing hair and also experiencing fatigue, weight gain, or mood shifts, thyroid dysfunction may be a contributing factor.

3. Emotional Stress and Telogen Effluvium

Stress is a powerful disruptor of the hair cycle. When the body experiences physical or emotional trauma, large numbers of follicles may shift from the growth phase into a short transition phase and then into the resting phase. This triggers telogen effluvium, often resulting in sudden shedding across the scalp.

You might suddenly notice hair loss in the shower or on your pillow. The condition is temporary but may persist for months if the stressor continues. Once the stressor is resolved, hair regrowth typically takes a few months. For many women, stress-related shedding impacts hair density and may lead to long-term thinning without early support.

4. Nutritional Gaps and Underlying Conditions

Iron deficiency, low vitamin D, and insufficient folic acid intake can all weaken the structure of the hair shaft and limit new hair production. Poor diet and underlying medical conditions like polycystic ovarian syndrome also influence hormone levels and androgen sensitivity, leading to slower growth or bald spots.

Some women may also experience anagen effluvium, which results in abrupt hair loss due to toxic exposure or medications. Other medications beyond those listed can also contribute to hair loss.

If you have a medical history of autoimmune disorders, metabolic imbalances, or nutritional deficiencies, blood tests can identify correctable issues affecting your hair. Depending on the underlying cause, other treatments may be necessary to effectively address hair loss.

5. Prescription Medications and Hair Loss

Many FDA-approved medications list hair loss as a possible side effect. These include:

  • Antidepressants
  • High blood pressure medications
  • Hormone therapy
  • Some acne treatments
  • Certain medications used during breastfeeding or post-pregnancy recovery

Women nursing an infant may also experience changes in hair texture and shedding due to hormone fluctuations and lower estrogen levels during lactation. These hormonal shifts can also affect breast milk production, further influencing hair health. Although shedding is often temporary, long-term loss can signal deeper hormonal changes.

If you are unsure whether your medication works with your body’s current hormonal state, talk to your provider about alternatives.

6. Genetics and the Role of Aging in Hair Loss

Genetics are a major factor in determining whether you’ll experience hair loss as you age. Female pattern hair loss, also known as androgenetic alopecia, is the most common cause of hair loss in women and is strongly influenced by family history. If your mother or grandmother had thinning hair or noticeable hair loss, you may be more likely to see similar changes.

As women get older, the natural hair cycle shifts. The growth phase, when hair grows actively, becomes shorter, while the resting phase lengthens. This means hair follicles spend less time producing new hair and more time at rest, resulting in thinner, shorter strands. Over time, hair follicles shrink and some may stop producing hair altogether, making it harder for hair to regrow and leading to overall thinning.

Female pattern baldness doesn’t usually cause complete bald spots like male pattern baldness, but it does lead to a gradual reduction in hair density, especially at the crown and part line. In fact, up to 30 million women in the United States experience this type of hair loss. Recognizing the genetic and age-related components of hair loss in women can help you seek early treatment and take steps to preserve more hair for longer.

7. Lifestyle Factors That Impact Hair Health

Your daily habits play a big role in the health and appearance of your hair. A balanced diet rich in essential nutrients—especially folic acid, vitamin D, and iron—can support healthy hair growth and help prevent thinning. These vitamins and minerals are crucial for keeping hair follicles strong and encouraging new hair to grow.

On the other hand, frequent use of heat styling tools, harsh chemical treatments, and tight hairstyles can weaken hair and lead to breakage or thinning. Stress is another major factor; high stress levels can trigger telogen effluvium, a condition where more hair enters the resting phase and sheds more easily. Practicing stress management techniques like meditation, yoga, or regular exercise can help reduce hair loss and support thicker hair.

Simple changes, such as using gentle hair products, protecting your hair from sun damage, and getting regular trims, can also make a difference. By taking care of your body and your hair, you can help maintain fuller, healthier hair as you age.

What Are the Best Treatment Options?

Treatment depends on the cause, and choosing the right hair loss treatment is essential. For many women, early intervention improves results. Hair loss treatments include options such as platelet-rich plasma, laser combs, topical solutions like minoxidil, and more, but results vary based on timing and consistency.

At MHA for Women, we offer TED Hair Restoration, a pain-free, non-surgical treatment that uses ultrasound-based technology to deliver regenerative serums into the scalp. This helps stimulate thicker hair, extend the growth phase, and support hair regrowth without needles or downtime.

Hair transplant and hair transplants are also available as surgical solutions for restoring hair growth, especially in cases of genetic or pattern baldness. These procedures, such as FUT and FUE, move hair follicles from donor areas to balding regions to achieve natural-looking results.

FDA-approved light therapies, like laser helmets and caps, are available to treat fphl (female pattern hair loss) and can be effective when used under medical supervision.

When using minoxidil, it is important to carefully apply minoxidil only to the scalp and avoid spreading it to other areas to prevent unwanted hair growing on the cheeks or forehead. A potential side effect of minoxidil is hair growing in unintended areas if not applied properly.

To see how the procedure works, visit what to expect during and after TED Hair Restoration.

Expert Recommendations: What the Cleveland Clinic Advises

When it comes to treating female pattern hair loss, the Cleveland Clinic recommends a comprehensive approach that combines medical treatments, lifestyle adjustments, and, in some cases, hair transplantation. For many women, FDA-approved medications like minoxidil are the first line of defense, helping to stimulate hair growth and slow down hair loss. Platelet-rich plasma (PRP) therapy is another promising option, using your own blood’s growth factors to encourage hair regrowth when injected into the scalp.

The Cleveland Clinic also emphasizes the importance of a healthy diet, stress reduction, and gentle hair care practices as part of an overall strategy to treat hair loss. For women experiencing significant or persistent hair loss, hair transplantation may be considered to restore hair growth and improve self-esteem.

Early intervention is key—starting treatment as soon as you notice hair loss can increase your chances of seeing real results. By following these expert recommendations, you can take proactive steps to treat hair loss, support hair regrowth, and feel more confident in your appearance.

Let’s Take the Guesswork Out of Hair Loss

If you’ve noticed changes in your hair and wonder what’s behind it, our women’s health specialists can help. We take a full look at your hormone levels, medical history, and lifestyle to uncover the root cause. As part of the diagnostic process, we may assess how many strands of hair you are losing daily to better understand your hair loss. Schedule a consultation to find the treatment that fits you best.

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